Systemic RNA oxidation can be used as a biomarker of infection in challenged with

Authors :: Ya-Ya, Pian
Jing-Jing, Nie
Chen-Chen, Wang
Qian, Liu
Zhen, Liu
Li-Qun, Zhang
Qiu-Geng, Ou-Yang
Guo-Qing, Fan
Lv-Tao, Zeng
Ya-Min, Dang
Ya-Qing, Ma
Wei, Zhang
Zhen-Xiang, Gao
Ji-Hong, Hu
Jian-Ping, Cai
Source :: Free radical research. 55(1)
Publication Year :: 2021
Abstract: More and more evidence support the concept that RNA oxidation plays a substantial role in the progress of multiple diseases; however, only a few studies have reported RNA oxidation caused by microbial pathogens. Urinary 8-oxo-7,8-dihydroguanosine (8-oxo-Gsn) and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dGsn), which are broadly used as indicators of oxidative damage of RNA and DNA, were analyzed in this study to determine which can be used as a biomarker of infection in challenged with

Subjects :: Male
Animals
RNA
Vibrio parahaemolyticus
Oxidation-Reduction
Biomarkers
Rats

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