Mutations in Noncoding

Authors :: Samah, El Ghamrasni
Rene, Quevedo
James, Hawley
Parisa, Mazrooei
Youstina, Hanna
Iulia, Cirlan
Helen, Zhu
Jeff P, Bruce
Leslie E, Oldfield
S Y Cindy, Yang
Paul, Guilhamon
Jüri, Reimand
Dave W, Cescon
Susan J, Done
Mathieu, Lupien
Trevor J, Pugh
Source :: Molecular cancer research : MCR. 20(1)
Publication Year :: 2021
Abstract: Whole-genome sequencing of primary breast tumors enabled the identification of cancer driver genes and noncoding cancer driver plexuses from somatic mutations. However, differentiating driver from passenger events among noncoding genetic variants remains a challenge. Herein, we reveal cancer-driver