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Nonresponse to high-dose bupropion for depression in a patient carrying

Authors :
Céline K, Stäuble
Markus L, Lampert
Thorsten, Mikoteit
Martin, Hatzinger
Kurt E, Hersberger
Henriette E, Meyer Zu Schwabedissen
Source :
Pharmacogenomics. 21(16)
Publication Year :
2020

Abstract

We report the case of a patient with major depression treated with high-dose bupropion due to prior detected subtherapeutic blood concentrations at standard dosing. Pharmacogenetic panel testing identified the patient as a carrier of the

Subjects

Subjects :
Adult
Male
Depressive Disorder
Genetic Variation
Polymorphism, Single Nucleotide
Cytochrome P-450 CYP2C19
Hospitalization
Cytochrome P-450 CYP2B6
Pharmacogenetics
Recurrence
Antidepressive Agents, Second-Generation
Humans
Treatment Failure
Bupropion
Alleles

Details

ISSN :
17448042
Volume :
21
Issue :
16
Database :
OpenAIRE
Journal :
Pharmacogenomics
Accession number :
edsair.pmid..........6f98f9f6892ba4a23de6cee3f06ab98c

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Authors Abstract Subjects Details