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[A Case of Ascending Colon Cancer with Lynch Syndrome Who Underwent XELOX Adjuvant Chemotherapy]
[A Case of Ascending Colon Cancer with Lynch Syndrome Who Underwent XELOX Adjuvant Chemotherapy]
- Source :
- Gan to kagaku ryoho. Cancerchemotherapy. 45(1)
- Publication Year :
- 2018
-
Abstract
- Lynch syndrome is an inherited syndrome with the development of the colorectal and various other cancers. Lynch syndrome is caused by mutations in the mismatch repair genes. A 33 year-old male underwent XELOX adjuvant chemotherapy for ascending colon cancer with Lynch syndrome. Although efficacy of 5-FU is not demonstrated in Lynch syndrome, MOSAIC trial had suggested a benefit from FOLFOX compared with 5-FU in patients who have colorectal cancer with Lynch syndrome. Oxaliplatin-based adjuvant chemotherapy can be a therapeutic option for colorectal cancer in lynch syndrome patients.
Details
- ISSN :
- 03850684
- Volume :
- 45
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Gan to kagaku ryoho. Cancerchemotherapy
- Accession number :
- edsair.pmid..........6fc6b47aa38ab170048504cb2a7aece7