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Discovery of Hexahydrofuro[3,2
- Source :
- Journal of medicinal chemistry. 65(15)
- Publication Year :
- 2022
-
Abstract
- Janus kinase 3 (JAK3) is a potential target for the treatment of hematological malignancies. Herein, we report the discovery of a series of new orally bioavailable irreversible JAK3 kinase inhibitors. The representative compound
Details
- ISSN :
- 15204804
- Volume :
- 65
- Issue :
- 15
- Database :
- OpenAIRE
- Journal :
- Journal of medicinal chemistry
- Accession number :
- edsair.pmid..........78640a488f5fd8916f688e91a8b71f0b