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Full-term pregnancy with embryos from donated oocytes in a 36-year-old woman allografted for chronic myeloid leukemia
- Source :
- Bone marrow transplantation. 13(4)
- Publication Year :
- 1994
-
Abstract
- We report the first case of full-term pregnancy arising from donated oocytes in a 36-year-old woman with chronic myeloid leukemia (CML), 6 years after allogeneic bone marrow transplantation (BMT) following total body irradiation (TBI) (12 Gy) and cyclophosphamide 120 mg/kg. The first attempt at implantation with her own cryopreserved ovocytes was unsuccessful. Thereafter, she became pregnant after donated oocyte implantation using estradiol and progesterone support replacing the defective ovarian function. The baby was normal. Unfortunately, 6 months later, she relapsed in chronic phase of CML.
- Subjects :
- Adult
Estradiol
Ovary
Infant, Newborn
Pregnancy Outcome
Primary Ovarian Insufficiency
Embryo Transfer
Tissue Donors
Pregnancy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia, Myeloid, Chronic-Phase
Oocytes
Humans
Female
Radiation Injuries
Cyclophosphamide
Infertility, Female
Progesterone
Whole-Body Irradiation
Bone Marrow Transplantation
Subjects
Details
- ISSN :
- 02683369
- Volume :
- 13
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Bone marrow transplantation
- Accession number :
- edsair.pmid..........79882fb903e24fa1f897ce50b0a261c1