Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M

Authors :: Plamen P, Christov
Robyn, Richie-Jannetta
Philip J, Kingsley
Anoop, Vemulapalli
Kwangho, Kim
Gary A, Sulikowski
Carmelo J, Rizzo
Amit, Ketkar
Robert L, Eoff
Carol A, Rouzer
Lawrence J, Marnett
Source :: Chemical research in toxicology. 34(12)
Publication Year :: 2021
Abstract: The lipid peroxidation product malondialdehyde and the DNA peroxidation product base-propenal react with dG to generate the exocyclic adduct, M

Subjects :: Molecular Structure
Tandem Mass Spectrometry
DNA Polymerase iota
Oligonucleotides
Deoxyguanosine
Humans
DNA-Directed DNA Polymerase
Chromatography, Liquid

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