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Prevalence of human herpesvirus 8 DNA in peripheral blood mononuclear cells of acute and chronic leukemia patients in Taiwan
- Source :
- FEMS immunology and medical microbiology. 61(3)
- Publication Year :
- 2011
-
Abstract
- Human herpesvirus 8 (HHV-8) is associated with the development of Kaposi's sarcoma and several other human malignancies. The prevalence of HHV-8 DNA in peripheral blood mononuclear cells (PBMCs) in Taiwanese leukemia populations has not been investigated. In this study, HHV-8 DNA was extracted from PBMCs, and detected in 10.29% of the leukemia cases and 8.94% of the relatives' cases. In addition, the prevalence of HHV-8 DNA in PBMCs was nonsignificantly associated with gender, age and leukemia subtypes. The study examines the prevalence of HHV-8 DNA in PBMCs in Taiwanese leukemia and can be applied in further epidemiological studies.
Details
- ISSN :
- 1574695X
- Volume :
- 61
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- FEMS immunology and medical microbiology
- Accession number :
- edsair.pmid..........80dd49fb16fd53fd3b9be5331a3ece7a