Radiolabeling of the antibody IgG M75 for epitope of human carbonic anhydrase IX by

Authors :: Adam, Čepa
Jan, Ráliš
Lenka, Marešová
Markéta, Kleinová
Daniel, Seifert
Irena, Sieglová
Vlastimil, Král
Miloslav, Polášek
Monika, Paurová
Milan, Lázníček
Ondřej, Lebeda
Source :: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 143
Publication Year :: 2018
Abstract: Human carbonic anhydrase IX is a membrane enzyme that is significantly expressed in some types of cancer cells, while copper radioisotopes offer wide range of diagnostic, therapeutic and theranostic properties. The work was focused on a new approach to the labelling of antibody IgG M75 for epitope human carbonic anhydrase IX with copper radioisotopes

Subjects :: Male
Immunoconjugates
Antibodies, Monoclonal
Mice, Nude
Mice
Copper Radioisotopes
Radioimmunodetection
Antigens, Neoplasm
Immunoglobulin G
Positron-Emission Tomography
Animals
Humans
Tissue Distribution
Radiopharmaceuticals
Carbonic Anhydrase IX
Colorectal Neoplasms
HT29 Cells

ISSN :: 18729800
Volume :: 143
Database :: OpenAIRE
Journal :: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
Accession number :: edsair.pmid..........8442e807c119e3a6ebecdf9865d7fc05

Tools