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The drug candidate, ADX71441, is a novel, potent and selective positive allosteric modulator of the GABA
- Source :
- Neuropharmacology. 114
- Publication Year :
- 2014
-
Abstract
- Positive allosteric modulation of the GABA
- Subjects :
- Male
Analgesics
Triazines
Pain
Anxiety
Motor Activity
Rats
Mice, Inbred C57BL
Rats, Sprague-Dawley
Mice
HEK293 Cells
Anti-Anxiety Agents
Bacterial Proteins
Receptors, GABA-B
Guanosine 5'-O-(3-Thiotriphosphate)
Muscle Spasticity
Rotarod Performance Test
Acetamides
Animals
Humans
Transcription Factors
Subjects
Details
- ISSN :
- 18737064
- Volume :
- 114
- Database :
- OpenAIRE
- Journal :
- Neuropharmacology
- Accession number :
- edsair.pmid..........86852781b8e5bef5a13ca53d508a0749