Back to Search
Start Over
Electronic communication of cells with a surface mediated by boronic acid saccharide interactions† †Electronic supplementary information (ESI) available: Experimental detail and supporting figures. See DOI: 10.1039/c5cc04311e Click here for additional data file
- Source :
- Chemical Communications (Cambridge, England)
- Publication Year :
- 2015
- Publisher :
- Royal Society of Chemistry, 2015.
-
Abstract
- Gold surfaces were molecularly tailored with a saccharide binding motif capable of covalently adhering cells. This facilitated communication via the macrophage membrane with implications for understanding mammalian cell signalling.<br />The fabrication of a molecularly tailored surface functionalised with a saccharide binding motif, a phenyl boronic acid derivative is reported. The functionalised surface facilitated the transfer of electrons, via unique electronic interactions mediated by the presence of the boronic acid, from a macrophage cell line. This is the first example of eukaryotic cellular-electrical communication mediated by the binding of cells via their cell–surface saccharide units.
- Subjects :
- Chemistry
Surface Properties
Carbohydrates
Electrons
Boronic Acids
Subjects
Details
- Language :
- English
- ISSN :
- 1364548X and 13597345
- Volume :
- 51
- Issue :
- 97
- Database :
- OpenAIRE
- Journal :
- Chemical Communications (Cambridge, England)
- Accession number :
- edsair.pmid..........8768fe4d628111c6ba9946bdc4d0d469