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Model to predict on-treatment restoration of functional HBV-specific CD8
- Source :
- Alimentary pharmacologytherapeutics. 55(12)
- Publication Year :
- 2022
-
Abstract
- Hepatitis B virus (HBV)-specific CD8To predict this response with variables involved in T-cell exhaustion for use as a treatment stopping tool.In NUC-treated CHBe(-) patients, we considered a functional response in cases with HBV-specific CD8We developed an LRM that predicted the presence of a proliferative type I cytokine-secreting CD8Short-term low-level antigen exposure and early long-term NUC treatment influence the restoration of a functional HBV-specific CD8
Details
- ISSN :
- 13652036
- Volume :
- 55
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Alimentary pharmacologytherapeutics
- Accession number :
- edsair.pmid..........880218a9cb8313af84afc968f1e7fefb