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Model to predict on-treatment restoration of functional HBV-specific CD8

Authors :
Julia, Peña-Asensio
Henar, Calvo
Joaquín, Miquel
Eduardo, Sanz-de-Villalobos
Alejandro, González-Praetorius
Miguel, Torralba
Juan-Ramón, Larrubia
Source :
Alimentary pharmacologytherapeutics. 55(12)
Publication Year :
2022

Abstract

Hepatitis B virus (HBV)-specific CD8To predict this response with variables involved in T-cell exhaustion for use as a treatment stopping tool.In NUC-treated CHBe(-) patients, we considered a functional response in cases with HBV-specific CD8We developed an LRM that predicted the presence of a proliferative type I cytokine-secreting CD8Short-term low-level antigen exposure and early long-term NUC treatment influence the restoration of a functional HBV-specific CD8

Details

ISSN :
13652036
Volume :
55
Issue :
12
Database :
OpenAIRE
Journal :
Alimentary pharmacologytherapeutics
Accession number :
edsair.pmid..........880218a9cb8313af84afc968f1e7fefb