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Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome

Authors :
Sergio, Martinez-Høyer
Yu, Deng
Jeremy, Parker
Jihong, Jiang
Angela, Mo
T Roderick, Docking
Nadia, Gharaee
Jenny, Li
Patricia, Umlandt
Megan, Fuller
Martin, Jädersten
Austin, Kulasekararaj
Luca, Malcovati
Alan F, List
Eva, Hellström-Lindberg
Uwe, Platzbecker
Aly, Karsan
Source :
Nature cell biology. 22(5)
Publication Year :
2019

Abstract

Interstitial deletion of the long arm of chromosome 5 (del(5q)) is the most common structural genomic variant in myelodysplastic syndromes (MDS)

Details

ISSN :
14764679
Volume :
22
Issue :
5
Database :
OpenAIRE
Journal :
Nature cell biology
Accession number :
edsair.pmid..........88475ecd05a5c1a2914b283040e04da8