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The evolution of mendelian randomization for investigating drug effects
- Source :
- PLoS Medicine
- Publication Year :
- 2022
- Publisher :
- Public Library of Science, 2022.
-
Abstract
- Dipender Gill and Stephen Burgess discuss the accompanying study by James Yarmolinsky and colleagues investigating the associations between genetically-proxied inhibition of antihypertensive drug targets and risk of common cancer subtypes using Mendelian randomization.
- Subjects :
- Drug Research and Development
ACE inhibitors
Epidemiology
Cardiology
Angiotensin-Converting Enzyme Inhibitors
Blood Pressure
Cardiovascular Medicine
Biochemistry
Medical Conditions
Risk Factors
Drug Discovery
Basic Cancer Research
Genetics
Medicine and Health Sciences
Humans
Antihypertensive Agents
Colorectal Cancer
Pharmacology
Cancer Drug Discovery
Cancer Risk Factors
Biology and Life Sciences
Cancers and Neoplasms
Drugs
Genetic Variation
Enzyme inhibitors
Cardiovascular Disease Risk
Mendelian Randomization Analysis
Antihypertensive Drugs
Oncology
Cardiovascular Diseases
Medical Risk Factors
Perspective
Enzymology
Colorectal Neoplasms
Genome-Wide Association Study
Subjects
Details
- Language :
- English
- ISSN :
- 15491676 and 15491277
- Volume :
- 19
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- PLoS Medicine
- Accession number :
- edsair.pmid..........8ae262f3c723dca74d51c5f4ffaea7d9