Back to Search Start Over

Longitudinal MRI-visible perivascular space (PVS) changes with long-duration spaceflight

Authors :
Kathleen E, Hupfeld
Sutton B, Richmond
Heather R, McGregor
Daniel L, Schwartz
Madison N, Luther
Nichole E, Beltran
Igor S, Kofman
Yiri E, De Dios
Roy F, Riascos
Scott J, Wood
Jacob J, Bloomberg
Ajitkumar P, Mulavara
Lisa C, Silbert
Jeffrey J, Iliff
Rachael D, Seidler
Juan, Piantino
Source :
Scientific reports. 12(1)
Publication Year :
2021

Abstract

Humans are exposed to extreme environmental stressors during spaceflight and return with alterations in brain structure and shifts in intracranial fluids. To date, no studies have evaluated the effects of spaceflight on perivascular spaces (PVSs) within the brain, which are believed to facilitate fluid drainage and brain homeostasis. Here, we examined how the number and morphology of magnetic resonance imaging (MRI)-visible PVSs are affected by spaceflight, including prior spaceflight experience. Fifteen astronauts underwent six T

Details

ISSN :
20452322
Volume :
12
Issue :
1
Database :
OpenAIRE
Journal :
Scientific reports
Accession number :
edsair.pmid..........8e34d6a05225660077d3d64df6ca3192