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A comparison of the clinical features and prognosis of pancreatic head cancer with that of other periampullary cancers

Authors :
Ye Min, Liang
Tao, Wang
Qi Long, Sun
Yu Feng, Cheng
Source :
Hepato-gastroenterology. 60(124)
Publication Year :
2012

Abstract

Our purpose was to compare the clinical features and prognosis of pancreatic head cancer with that of other periampullary cancers.The medical records of 82 patients (mean age of 61.67±10.52 years) with ductal adenocarcinoma of the head of pancreas and 73 patients (mean age of 60.52±11.72 years) with other periampullary adenocarcinomas, all of whom had received radical surgery, were retrospectively analyzed.There were no significant differences in age and gender between the groups (both, p0.05). However, there were significant differences in lymph node metastasis, TNM stage, clear surgical margins, tumor size, and neural invasion between the 2 groups (all p0.05). Patients with pancreatic head adenocarcinoma had significantly higher red blood cell (RBC) count and hemoglobin (Hb), albumin and pre-albumin levels, and higher platelet and white blood cell (WBC) counts than the patients with other periampullary adenocarcinomas (all p0.05). No differences in carcinoembryonic antigen (CEA) or CA19-9 were noted between the groups. The 1-year survival rates were not different between the groups (p=0.299).Pancreatic head carcinoma has different clinical manifestations and biological features than other periampullary cancers.

Details

ISSN :
01726390
Volume :
60
Issue :
124
Database :
OpenAIRE
Journal :
Hepato-gastroenterology
Accession number :
edsair.pmid..........93d32a68a79b18d77b1835dddd766a46