Comprehensive and comparative exploration of the Atp7b

Authors :: Maud, Lacombe
Michel, Jaquinod
Lucid, Belmudes
Yohann, Couté
Claire, Ramus
Florence, Combes
Thomas, Burger
Elisabeth, Mintz
Justine, Barthelon
Vincent, Leroy
Aurélia, Poujois
Alain, Lachaux
France, Woimant
Virginie, Brun
Source :: Metallomics : integrated biometal science. 12(2)
Publication Year :: 2019
Abstract: Wilson's disease (WD), a rare genetic disease caused by mutations in the ATP7B gene, is associated with altered expression and/or function of the copper-transporting ATP7B protein, leading to massive toxic accumulation of copper in the liver and brain. The Atp7b