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[Study on the inhibitory effect of Reduqing Oral Liquid on respiratory syncytial virus in vitro]

Authors :
Sheng-Hai, Huang
Xiao-Liang, Feng
Wei, Liu
Source :
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 32(4)
Publication Year :
2009

Abstract

To explore the antiviral effect of Reduqing Oral Liquid on respiratory syncytial virus (RSV).The anti-RSV effect of Reduqing Oral Liquid in Hep-2 cell culture was investigated by the cytopathic effect (CPE) inhibition assay and MTT assay, with ribavirin as the positive control drug.Reduqing Oral Liquid was effectively antiviral agent for RSV in a concentration-dependent manner in vitro. The median toxic concentration (TC50) was 9182.4 mg/L, the median effective concentration (EC50) was 559.8 mg/L and the treatment index (TI) was 16.4.Reduqing Oral Liquid has obvious inhibitory effect on RSV in vitro.

Details

ISSN :
10014454
Volume :
32
Issue :
4
Database :
OpenAIRE
Journal :
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Accession number :
edsair.pmid..........962479f7dc336e8578a92844c4965f2c