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Ultrasonic-assisted synthesis and DNA interaction studies of two new Ru complexes; RuO

Authors :
Jun-Jie, Xue
Fahime, Bigdeli
Jian-Ping, Liu
Mao-Lin, Hu
Ali, Morsali
Source :
Nanomedicine (London, England). 13(21)
Publication Year :
2018

Abstract

To study of the interactions of two new ruthenium(II) complexes (C1 and C2) with calf thymus (CT)-DNA; production of RuOComplex C1 was characterized by x-ray crystallography. The binding of the complexes with (CT)-DNA was studied using techniques that include electronic absorption spectra, fluorescence and redox behavior. The preparation of RuOThe interaction mode of DNA with complexes is the type of electrostatic. It was revealed that sonication of the samples, before thermal decomposition, has been affected the morphologies and sizes of the resulting nanoparticles.The complexes are capable of interaction with DNA molecules and they have a good potential to prepare nanostructures.

Details

ISSN :
17486963
Volume :
13
Issue :
21
Database :
OpenAIRE
Journal :
Nanomedicine (London, England)
Accession number :
edsair.pmid..........98bef7e89b52bc0db8535402b04343f3