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NINJ1 mediates plasma membrane rupture during lytic cell death

Authors :
Nobuhiko, Kayagaki
Opher S, Kornfeld
Bettina L, Lee
Irma B, Stowe
Karen, O'Rourke
Qingling, Li
Wendy, Sandoval
Donghong, Yan
Jing, Kang
Min, Xu
Juan, Zhang
Wyne P, Lee
Brent S, McKenzie
Gözde, Ulas
Jian, Payandeh
Merone, Roose-Girma
Zora, Modrusan
Rohit, Reja
Meredith, Sagolla
Joshua D, Webster
Vicky, Cho
T Daniel, Andrews
Lucy X, Morris
Lisa A, Miosge
Christopher C, Goodnow
Edward M, Bertram
Vishva M, Dixit
Source :
Nature. 591(7848)
Publication Year :
2020

Abstract

Plasma membrane rupture (PMR) is the final cataclysmic event in lytic cell death. PMR releases intracellular molecules known as damage-associated molecular patterns (DAMPs) that propagate the inflammatory response

Details

ISSN :
14764687
Volume :
591
Issue :
7848
Database :
OpenAIRE
Journal :
Nature
Accession number :
edsair.pmid..........99a21a561390a8ed6124a54ef201cc30