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Clinical Characteristics and Magnetic Resonance Imaging-Based Prediction of the KLF4

Authors :
Niklas, von Spreckelsen
Natalie, Waldt
Marco, Timmer
Lukas, Goertz
David, Reinecke
Kai, Laukamp
Lenhard, Pennig
Stefan, Grau
Martina, Deckert
Elmar, Kirches
Pantelis, Stavrinou
Christian, Mawrin
Roland, Goldbrunner
Source :
World neurosurgery. 154
Publication Year :
2021

Abstract

Meningioma is the most common primary brain tumor in adults. In recent years, several non-neurofibromin 2 mutations, i.e., AKT1, SMO, TRAF7, and KLF4 mutations, specific for meningioma have been identified. This study aims to analyze the clinical impact and imaging characteristics of the KLF4Clinical, neuropathologic, and imaging data of 170 patients who underwent meningioma resection between 2013 and 2018 were retrospectively collected and tumors were analyzed for the presence of the KLF4Eighteen (10.6%) of the meningiomas carried the KLF4The KLF4

Details

ISSN :
18788769
Volume :
154
Database :
OpenAIRE
Journal :
World neurosurgery
Accession number :
edsair.pmid..........a52a54b517cdbdbbc3b08b12810b7a56