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[Isoenzymes of gammaglutamyltransferase in patients with obstructive and hepatocellular icterus]

[Isoenzymes of gammaglutamyltransferase in patients with obstructive and hepatocellular icterus]

Authors :
K, Anic
A, Ivandic
L, Peric
M, Fijacko
M, Volaric
T, Bacun
D, Kovacic
L, Getto
Source :
Wiener medizinische Wochenschrift (1946). 149(12)
Publication Year :
1999

Abstract

We have been determining the GGT IE isoenzyme in patients with hepatitis A and B with decomposed liver cirrhosis, with obstructive hepatitis caused by the gall stones. In patients with hepatitis A and B the IE is located between albumin and betaglobulin, as well as in patients with obstructive hepatitis caused by the gall stones; in the latter partly between Alpha 1 and Alpha 2 globulin. In patients with decompensated liver cirrhosis (37.7% of the patients) there was IE activity 100% in Alpha 2 globulin area; in 6.25% of patients the activity was in the prealbumin area. In patients with secondary liver tumors we got a rather high increase of the GGT IE activity in Alpha 1 globulin area, in 77.7% of the patients even 80 to 100%. In some patients with disease progression we noticed the GGT IE activity in Beta globulin area. The results in primary liver malignomas were different. In 68.5% of the patients the GGT IE activity dominated in Alpha 1 globulin area.

Details

Language :
German
ISSN :
00435341
Volume :
149
Issue :
12
Database :
OpenAIRE
Journal :
Wiener medizinische Wochenschrift (1946)
Accession number :
edsair.pmid..........aa0b4deb006b49e11e46f87d7dabda3e