[Solubility and degree of hemolysis as methods for the in vitro evaluation of dental filling materials]

For the biological examination of dental resin filling materials, a solubility and hemolysis test is recommended as an in-vitro testing method. Solubility and degree of hemolysis were examined in various filling materials based on MMA and BIS-GMA. It was found that, at the beginning, solubility was considerably higher in MMA-containing materials than in the BIS-GMA systems, and that after a while the conditions were reversed. The degree of hemolysis decreased in the following order with the individual materials: 1. Posite, Sevriton, Adatpic, 2. Epoxylite, Smile, Palakav, 3. MMA-BPO/Amin and MMA-TBBO. Comparison between the MMA and BIS-GMA monomers showed that corresponding to the same molar amounts, BIS-GMA materials developed a higher degree of hemolysis.