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Bifunctional Naphtho[2,3
- Source :
- Journal of medicinal chemistry. 63(14)
- Publication Year :
- 2020
-
Abstract
- Human dihydroorotate dehydrogenase (
- Subjects :
- Male
Membrane Potential, Mitochondrial
Mice, Inbred BALB C
Oxidoreductases Acting on CH-CH Group Donors
Molecular Structure
Dihydroorotate Dehydrogenase
Antineoplastic Agents
Apoptosis
Mice, SCID
Triazoles
Molecular Docking Simulation
Rats, Sprague-Dawley
Structure-Activity Relationship
Cell Line, Tumor
S Phase Cell Cycle Checkpoints
Animals
Humans
Female
Drug Screening Assays, Antitumor
Enzyme Inhibitors
Reactive Oxygen Species
Cell Proliferation
Naphthoquinones
Protein Binding
Subjects
Details
- ISSN :
- 15204804
- Volume :
- 63
- Issue :
- 14
- Database :
- OpenAIRE
- Journal :
- Journal of medicinal chemistry
- Accession number :
- edsair.pmid..........c461431e40ee9dbb7c922b89bdbb07ea