Interactions between PAMAM-NH

Authors :: Xueke, Gao
Minjun, Ma
Christian Marcus, Pedersen
Rui, Liu
Zhenzhou, Zhang
Honghong, Chang
Yan, Qiao
Yingxiong, Wang
Source :: Chemistry, an Asian journal. 16(22)
Publication Year :: 2021
Abstract: Despite being used as an anti-leukemic drug, the poor solubility of 6-mercaptopurine (6-MP) limits its use in topical and parenteral applications. Dendrimers are commonly used as drug carriers to improve their solubility in aqueous solution. In this work, the interactions between 6-MP and the amine-terminated poly(amidoamine) dendrimers (PAMAM-NH

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