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Chemical Modification for Proteolytic Stabilization of the Selective α

Authors :
Daniela, Comegna
Antonella, Zannetti
Annarita, Del Gatto
Ivan, de Paola
Luigi, Russo
Sonia, Di Gaetano
Annamaria, Liguoro
Domenica, Capasso
Michele, Saviano
Laura, Zaccaro
Source :
Journal of medicinal chemistry. 60(23)
Publication Year :
2017

Abstract

Herein, we report the synthesis and biological characterization of the new peptide ψRGDechi as the first step toward novel-targeted theranostics in melanoma. This pseudopeptide is designed from our previously reported RGDechi peptide, known to bind selectively α

Details

ISSN :
15204804
Volume :
60
Issue :
23
Database :
OpenAIRE
Journal :
Journal of medicinal chemistry
Accession number :
edsair.pmid..........ca874725f448ca4c9a322345d7c91f26