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[Hydroxychloroquine and chloroquine for COVID-19: no evidence of effectiveness]
- Source :
- Nederlands tijdschrift voor geneeskunde. 164
- Publication Year :
- 2020
-
Abstract
- On 3 March 2020, the document 'Drug treatment options for patients with COVID-19 (infections with SARS-CoV-2)' was published on the website of the Dutch Working Party on Antibiotic Policy (StichtingWerkgroepAntibioticabeleid, SWAB). Based on a 7-step analysis of the literature, hydroxychloroquine (HCQ) and chloroquine (CQ) were initially included in the SWAB document as possible drug treatments for hospitalised adult COVID-19 patients. However, recent weeks have seen the publication of the results of various studies into the effectiveness of treatment with HCQ and CQ in patients with COVID-19. On the basis of these results, we conclude that there is insufficient evidence to consider HCQ and CQ as meaningful treatment options in patients with COVID-19. Clinically relevant QTc prolongation occurs in at least 1 in 10 COVID-19 patients treated with HCQ or HQ.
Details
- Language :
- Dutch; Flemish
- ISSN :
- 18768784
- Volume :
- 164
- Database :
- OpenAIRE
- Journal :
- Nederlands tijdschrift voor geneeskunde
- Accession number :
- edsair.pmid..........cbb0ce37001f3cdd1fa5a4bc9e8625d4