[CORRECTION OF INTRAABDOMINAL PRESSURE IN RATS IN AN ACUTE PANCREATITIS, USING INFUSION OF MYORELAXANT OF A DURABLE ACTION PIPECURONIUM BROMIDE]

Authors :: A S, Morgun
A I, Sukhodolya
O V, Kabanov
S A, Sukhodolya
M, Falaleyeva
T V, Beregova
Source :: Klinichna khirurhiia. (1)
Publication Year :: 2018
Abstract: Impact of a durable action of myorelaxant pipecuronium bromide on intraabdominal pressure (IAP) in rats in experimentally simulated acute peritonitis was studied. In the rats in purulent pancreatitis, іnduced by L-аrginin, IAP was in 4,5 times high (p0.001), than in intact laboratory animals. Pipecuronium bromide have lowered IAP by 33.4%, witnessing efficacy of application of myorelaxants in treatment of intraabdominal hypertension in purulent pancreatitis.

Subjects :: Pipecuronium
Acute Disease
Animals, Outbred Strains
Animals
Intra-Abdominal Hypertension
Peritonitis
Arginine
Injections, Intramuscular
Injections, Intraperitoneal
Neuromuscular Nondepolarizing Agents
Rats

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