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[T-cell costimulation. Basic mechanisms and new aspects]

Authors :
A, Hutloff
Source :
Zeitschrift fur Rheumatologie. 70(7)
Publication Year :
2011

Abstract

Recent publications regarding the function of the T-cell costimulators CD226 and TIGIT as well as the identification of the new costimulatory ligand VISTA are of great interest for an understanding of autoimmune diseases. Both systems display striking similarities to the well-established costimulators CD28/CTLA-4 and PD-1.

Subjects

Subjects :
Antigens, Differentiation, T-Lymphocyte
T-Lymphocytes
Programmed Cell Death 1 Receptor
Lymphocyte Activation
Recombinant Proteins
Autoimmune Diseases
Mice
Costimulatory and Inhibitory T-Cell Receptors
Animals
Humans
CTLA-4 Antigen
Receptors, Immunologic
Carrier Proteins
Signal Transduction

Details

Language :
German
ISSN :
14351250
Volume :
70
Issue :
7
Database :
OpenAIRE
Journal :
Zeitschrift fur Rheumatologie
Accession number :
edsair.pmid..........d0d480cfc1951fb1d30598f345a0de2a

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Authors Abstract Subjects Details