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[Clinical Features and Prognosis of t(8;21) AML Patients in China: A Multicenter Retrospective Study]

Authors :
Dan, Gong
Wei, Li
Liang-Ding, Hu
Jian-Min, Luo
Jian-Liang, Shen
Mei-Yun, Fang
Qing-Ming, Yang
Heng-Xiang, Wang
Xiao-Yan, Ke
Hui-Ren, Chen
Zhao, Wang
Hui, Liu
Feng, Liu
Yi-Gai, Ma
Jing-Wen, Wang
Hong-Hua, Li
Quan-Shun, Wang
Yu, Jing
Xiao-Ning, Gao
Li-Ping, Dou
Yong-Hui, Li
Li, Yu
Source :
Zhongguo shi yan xue ye xue za zhi. 25(4)
Publication Year :
2017

Abstract

To summarize the clinical characteristics of peripheral blood, immune phenotypes, fusion genes and cytogenetics of patients with t(8;21) acute myeloid leukemia(AML) through the retrospective analysis of 586 patients with t(8;21) AML from 15 blood disease research centers in Northern area of China.The factors affecting prognosis of patients with t(8;21) AML were investigated by using univariate and multivariate COX regression.The immune type of t(8;21) AML patients was mainly with HLA-DRThe clinical features of t(8;21) AML patients in China are similar to those in other countries, WBC≤3.5×10

Details

ISSN :
10092137
Volume :
25
Issue :
4
Database :
OpenAIRE
Journal :
Zhongguo shi yan xue ye xue za zhi
Accession number :
edsair.pmid..........d265e20af1a642ae912fee80b02b4d63