CD169

Authors :: Xin, Chen
Yuhan, Zheng
Siming, Liu
Wenjing, Yu
Zhiduo, Liu
Source :: European journal of immunologyReferences. 52(10)
Publication Year :: 2022
Abstract: Follicular dendritic cells (FDCs) are a specialized type of stromal cells that exclusively reside in B-cell follicles. When inflammation occurs, the FDC network is reorganized to support germinal center (GC) polarization into the light zone (LZ) and dark zone (DZ). Despite the indispensable role of FDCs in supporting humoral responses, the FDC regulatory requirements remain incompletely defined. In this study, we unexpectedly observed an accumulation of CD169