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Deficiency of Omentin-1 leads to delayed fracture healing through excessive inflammation and reduced CD31

Authors :
Shi-Kai, Feng
Tuan-Hui, Chen
Hong-Ming, Li
Jia, Cao
Dong-Biao, Liu
Shan-Shan, Rao
Jiang-Hua, Liu
Yan, Zhang
Zhen-Xing, Wang
You-You, Li
Yi-Juan, Tan
Yi-Wei, Liu
Chun-Gu, Hong
Zi-Qi, Yan
Meng-Lu, Chen
Yi-Yi, Wang
Hao, Yin
Ling, Jin
Hui, Xie
Zheng-Guang, Wang
Yong, Zhou
Source :
Molecular and cellular endocrinology. 534
Publication Year :
2020

Abstract

Fracture healing is a complicated process affected by many factors, such as inflammatory responses and angiogenesis. Omentin-1 is an adipokine with anti-inflammatory properties, but whether omentin-1 affects the fracture healing process is still unknown. Here, by using global omentin-1 knockout (omentin-1

Details

ISSN :
18728057
Volume :
534
Database :
OpenAIRE
Journal :
Molecular and cellular endocrinology
Accession number :
edsair.pmid..........db2e76a80d6f8e2f7f37ea238b965483