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[PET/CT and biochemical recurrence of prostate adenocarcinoma: Added value of

Authors :
M, Gauthé
O, Belissant
A, Girard
J, Zhang Yin
J, Ohnona
A-S, Cottereau
V, Nataf
S, Balogova
D, Pontvert
T, Lebret
B, Guillonneau
O, Cussenot
J-N, Talbot
Source :
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 27(8-9)
Publication Year :
2017

Abstract

Since April 201, we have introduced PET/CT using a ligand of prostate-specific membrane antigen labeled with gallium-68 (PSMA-11). We aimed to evaluate its positivity rate and impact in patients presenting biochemical recurrence of prostate cancer whosePatients were prospectively included between April and December 2016. PET/CT was performed 60min after injection of 2MBq/kg of body mass ofThirty-three patients were included. The mean PSA serum level measured on the month of the PSMA-11 PET/CT was 2,8ng/mL. Twenty-five (76%) PSMA-11 PET/CT were positive, 7 (21%) negative and 1 (3%) equivocal. Of 11 patients whose FCH PET/CT showed equivocal foci, PSMA-11 PET/CT confirmed those foci in 5 cases. Follow-up was available for 18 patients (55%). PSMA-11 PET/CT results led to a change in management in 12 patients (67%).5.

Details

Language :
French
ISSN :
11667087
Volume :
27
Issue :
8-9
Database :
OpenAIRE
Journal :
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie
Accession number :
edsair.pmid..........dc411cdc2cfbfdda2ba110f89c398cde