[Effect of endoscopic sinus surgery on asthmatic patients with chronic sinusitis and nasal polyps]

To explore the effect of endoscopic sinus surgery (ESS) in patients with chronic rhinosinusitis and asthma.Forty-two patients with asthma who underwent ESS and control group were investigated. Interleukin-4 (IL-4), interferon-gamma (IFN-gamma), soluble interleukin-2 receptor (sIL-2R) and soluble CD23 (sCD23) levels in culture supernatant of peripheral blood mononuclear cell (PBMC) were determined by enzyme-linked immunosorbent assay (ELISA).Of these 42 patients 32 (76%), their asthma was relieved greatly after ESS comparing with that before ESS. 14 of 21 patients (67%) taken regular medication for asthma before ESS reported that less medicine was used after operation.This study demonstrates that ESS has a favorable effect on asthma in patients with symptomatic chronic sinusitis.