Structural basis of ligand recognition at the human MT

Authors :: Benjamin, Stauch
Linda C, Johansson
John D, McCorvy
Nilkanth, Patel
Gye Won, Han
Xi-Ping, Huang
Cornelius, Gati
Alexander, Batyuk
Samuel T, Slocum
Andrii, Ishchenko
Wolfgang, Brehm
Thomas A, White
Nairie, Michaelian
Caleb, Madsen
Lan, Zhu
Thomas D, Grant
Jessica M, Grandner
Anna, Shiriaeva
Reid H J, Olsen
Alexandra R, Tribo
Saïd, Yous
Raymond C, Stevens
Uwe, Weierstall
Vsevolod, Katritch
Bryan L, Roth
Wei, Liu
Vadim, Cherezov
Source :: Nature. 569(7755)
Publication Year :: 2018
Abstract: Melatonin (N-acetyl-5-methoxytryptamine) is a neurohormone that maintains circadian rhythms

Subjects :: Models, Molecular
Lasers
Receptor, Melatonin, MT1
Electrons
Ligands
Antidepressive Agents
Substrate Specificity
Molecular Docking Simulation
Structure-Activity Relationship
Indenes
Acetamides
Mutation
Receptor, Serotonin, 5-HT2C
Humans
Amino Acid Sequence
Crystallization
Melatonin

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