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[Analysis of serologic typing error for HLA-A and HLA-B in Chinese]

[Analysis of serologic typing error for HLA-A and HLA-B in Chinese]

Authors :
Yu-Dong, Dai
Qi-Jun, Sun
Yi-Hong, Zhang
Hong, Yuan
Bo, Meng
Source :
Zhongguo shi yan xue ye xue za zhi. 10(5)
Publication Year :
2003

Abstract

Serological mistypings of HLA-A and HLA-B in 27 cases were analyzed. The results showed that for HLA-A and HLA-B typing, the rates of incorrect antigen assignments were significantly higher than rates of antigen misses (P0.05), but there was no significant difference between HLA-A and HLA-B typings. The frequencies of miss-assigned HLA-A and HLA-B specificities were A1 (66.7%), A3 (50.0%), A11 (13.5%), A9 (11.8%), A19 (7.1%), and B16 (50.0%), B48 (43.9%), B15 (16.7%), B40 (11.1%), B13 (10.0%) and B17 (9.1%). In conclusion, the serologic and DNA-based typing techniques should be reciprocally complementary in HLA-A and HLA-B typing.

Details

ISSN :
10092137
Volume :
10
Issue :
5
Database :
OpenAIRE
Journal :
Zhongguo shi yan xue ye xue za zhi
Accession number :
edsair.pmid..........e40367ccb5b96afa495533812679033f