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[Identification of chemical constituents in qiliqiangxin capsule by UPLC-Q-TOF/MS(E)]

Authors :
Li-ping, Kang
Yang, Zhao
He-shui, Yu
Yi-xun, Liu
Cheng-qi, Xiong
Da-wei, Tan
Ji-ming, Jia
Hong-tao, Wang
Shu-yan, Tian
Bai-Ping, Ma
Source :
Yao xue xue bao = Acta pharmaceutica Sinica. 46(10)
Publication Year :
2012

Abstract

In order to clarify the chemical constituents in Qiliqiangxin capsule, a rapid ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry (UPLC-Q-TOF/MS(E)) method was established. Forty peaks were identified on line using this method. The herbal sources of these peaks were assigned. The results implied that triterpenoid saponins, flavonoid glycosides, C21-steroids and phenolic acids were included in the main components of Qiliqiangxin capsule. The method is simple and rapid for elucidation of the constituents of Qiliqiangxin capsule and the results are useful for the quality control of Qiliqiangxin capsule.

Details

ISSN :
05134870
Volume :
46
Issue :
10
Database :
OpenAIRE
Journal :
Yao xue xue bao = Acta pharmaceutica Sinica
Accession number :
edsair.pmid..........e767dccff586986213f28b3507a9c47b