Excessive

Authors :: Priya, Umapathi
Olurotimi O, Mesubi
Partha S, Banerjee
Neha, Abrol
Qinchuan, Wang
Elizabeth D, Luczak
Yuejin, Wu
Jonathan M, Granger
An-Chi, Wei
Oscar E, Reyes Gaido
Liliana, Florea
C Conover, Talbot
Gerald W, Hart
Natasha E, Zachara
Mark E, Anderson
Source :: Circulation. 143(17)
Publication Year :: 2021
Abstract: Heart failure is a leading cause of death worldwide and is associated with the rising prevalence of obesity, hypertension, and diabetes.We developed 2 new transgenic mouse models with myocardial overexpression of OGT and OGA to controlWe found that OGT transgenic hearts showed increasedOur data provide evidence that excessive