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[Correlation of adiponectin, monocyte chemoattractant protein-1, and endothelial function to vascular remodeling in coronary in-stent restenosis]
- Source :
- Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 30(4)
- Publication Year :
- 2010
-
Abstract
- To investigate the correlation between vascular remodeling index (RI) and serum adiponectin, plasma monocyte chemoattractant protein-1 (MCP-1), endothelial function and evaluate the mechanism of coronary in-stent restenosis.RI 6 months after percutaneous coronary intervention (PCI), serum adiponectin, plasma MCP-1 and flow-mediated dilation (FMD) before and 3 days,6 months after PCI were measured in 30 patients with and 30 without coronary in-stent restenosis.Compared with patients without restenosis and those with restenosis before PCI, the patients with coronary in-stent restenosis showed significantly increased plasma MCP-1 3 days and 6 months after PCI (P0.05) and reduced RI 6 months after PCI, serum adiponectin and FMD 3 days and 6 months after PCI (P0.05). RI was positively correlated to serum adiponectin and FMD and inversely to MCP-1.The occurrence of coronary in-stent restenosis is the result of the interrelations between multiple factors.
Details
- ISSN :
- 16734254
- Volume :
- 30
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Nan fang yi ke da xue xue bao = Journal of Southern Medical University
- Accession number :
- edsair.pmid..........ea4fa288f3006d1b7d953d9b3e9d27b9