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Report: Safety and toxicological evaluation of herbal formulation on rodents

Authors :
Farzana, Sadaf
Sumbul, Shamim
Rubeena, Saleem
Navaidul, Zafar
Source :
Pakistan journal of pharmaceutical sciences. 31(6)
Publication Year :
2018

Abstract

Herbal medicines are still most popular, abundant and affordable remedies for curing various ailments. Garlina is one of the herbal formulations of Hamdard Laboratories (waqf) Pakistan used to treat cardiovascular diseases and elevated sugar level. However, there is no scientific data available regarding the potential toxicity. Therefore, the present study was to assess the acute and sub-chronic toxicity in rats. The single dose of Garlina 5000mg/kg were administered orally and observed for 14 days. A sub-chronic toxicity test was performed at 2000mg/kg of Garlina daily for 30 days. Control rats received saline. The biochemical, hematological and histopathological analysis was carried out. The acute toxicity LD

Details

ISSN :
1011601X
Volume :
31
Issue :
6
Database :
OpenAIRE
Journal :
Pakistan journal of pharmaceutical sciences
Accession number :
edsair.pmid..........eeb667711f15326f788be167b34fd9df