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In Vitro

Authors :
Ji-Yeon, Kang
Hong-Yeol, Choi
Dong-Il, Kim
Ohsuk, Kwon
Doo-Byoung, Oh
Source :
Journal of microbiology and biotechnology. 31(1)
Publication Year :
2020

Abstract

Enzyme replacement therapy for lysosomal storage diseases usually requires recombinant enzymes containing mannose-6-phosphate (M6P) glycans for cellular uptake and lysosomal targeting. For the first time, a strategy is established here for the in vitro mannosyl-phosphorylation of high-mannose type

Details

ISSN :
17388872
Volume :
31
Issue :
1
Database :
OpenAIRE
Journal :
Journal of microbiology and biotechnology
Accession number :
edsair.pmid..........ef8fc98b2e57b2eca1f828450168a31b