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Anti-allergic effect of the Src family kinase inhibitor saracatinib

Authors :
K, Yamaki
M, Terashi
S, Ogura
S, Inoue
N, Naka
T, Nakagaki
N, Oka
Y, Koyama
Source :
Die Pharmazie. 75(7)
Publication Year :
2020

Abstract

The aim of this study was to evaluate the anti-anaphylactic and anti-allergic potentials of saracatinib, a Src family kinase inhibitor that was already shown to be safe in clinical trials when it was used as an anti-cancer drug. Using

Subjects

Subjects :
Male
Mice, Hairless
Cell Survival
Immunoglobulin E
Cell Line
Rats
Disease Models, Animal
Mice
src-Family Kinases
Anti-Allergic Agents
Quinazolines
Animals
Benzodioxoles
Mast Cells
Enzyme Inhibitors
Phosphorylation
Anaphylaxis

Details

ISSN :
00317144
Volume :
75
Issue :
7
Database :
OpenAIRE
Journal :
Die Pharmazie
Accession number :
edsair.pmid..........f121271ee5713929ce70d99dde9d55f6

Tools

Authors Abstract Subjects Details