[The episodes of spreading depression during focal cerebral ischemia in rats and the effects of electroacupuncture]

To investigate the effects of electroacupuncture on the episodes of spreading depression (SD) in Wistar rats during focal cerebral ischemia.A model of the middle cerebral artery occlusion (MCAo) in Wistar rats was performed with the intraluminal filament occlusion. The episodes of SD in focal cerebral ischemia within 3 hours and the effects of electroacupuncture on "He gu" point (LI 4) were detected using neuroelectrophysiological method and neuropathological method.Electroacupuncture can reduce the episodes of SD during focal cerebral ischemia.Electroacupuncture can reduce the infarct volume of the focal cerebral ischemia, its mechanism may relate to reducing the episodes of SD during focal cerebral ischemia.