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Neuro-protective effects of nano-formulated hesperetin in a traumatic brain injury model of
- Source :
- Drug and chemical toxicology. 45(2)
- Publication Year :
- 2020
-
Abstract
- Understanding the mechanism behind neuronal regeneration is critical for treating ischemic stroke and traumatic brain injury. The presence of neural stem cells in and around the sub-ventricular zone of human and also in zebrafish is evidenced. In this current study, the neuro-protective potential of nano-formulated hesperetin on injury-induced neurogenesis in zebrafish was assessed. Nanoformulation of hesperetin was prepared by anti-solvent precipitation technique using sodium dodecyl sulfate (SDS) as the stabilizing agent. The synthesized particles were characterized using SEM, DLS, XRD and FT-IR. Anti-oxidant capacity of nano hesperetin (nHST) in
Details
- ISSN :
- 15256014
- Volume :
- 45
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Drug and chemical toxicology
- Accession number :
- edsair.pmid..........f6ce8000c51d9241723a380d9eea9b7c