Back to Search Start Over

An IL6-Adenosine Positive Feedback Loop between CD73

Authors :
Guoming, Hu
Pu, Cheng
Jun, Pan
Shimin, Wang
Qiannan, Ding
Zhou, Jiang
Lu, Cheng
Xuan, Shao
Liming, Huang
Jian, Huang
Source :
Cancer immunology research. 8(10)
Publication Year :
2019

Abstract

The tumor microenvironment induces immunosuppression via recruiting and expanding suppressive immune cells such as regulatory T cells (Treg) to promote cancer progression. In this study, we documented that tumor-infiltrating CD73

Subjects

Subjects :
Feedback, Physiological
Extracellular Matrix Proteins
Adenosine
Cancer-Associated Fibroblasts
Interleukin-6
Transforming Growth Factor beta
Tumor Microenvironment
Humans
Breast Neoplasms
Female
GPI-Linked Proteins
5'-Nucleotidase
Intraepithelial Lymphocytes

Details

ISSN :
23266074
Volume :
8
Issue :
10
Database :
OpenAIRE
Journal :
Cancer immunology research
Accession number :
edsair.pmid..........f936fbdb61facf3b10d7eef62b3b4c33

Tools

Authors Abstract Subjects Details