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[Allergic diseases in children and farming environment]
- Source :
- Revue des Maladies Respiratoires, Revue des Maladies Respiratoires, 2010, 27 (10), pp.1195-220. ⟨10.1016/j.rmr.2010.10.002⟩
- Publication Year :
- 2010
-
Abstract
- International audience; INTRODUCTION: Children living in rural areas had lower prevalence of allergies than children from cities, in relation to farming exposure. STATE OF ART: Exposure to farm animals and consumption of raw milk appear to play an important role in the protection afforded by the agricultural environment, and this at different stages of child development. The mechanisms involved in these effects are still controversial, and recent publications cast doubt on the role of endotoxins initially suggested. It seems that exposure to indoor air pollution, characterized by excessive biocontaminants (mold, allergens...) is a key element in the development of allergic diseases. PERSPECTIVES: The establishment of cohort studies, a better assessment of exposure to pollution at home but also in farm buildings and the study of gene-environment interactions should improve the knowledge on the protective effect towards allergy of farming environment. CONCLUSIONS: The farming environment, very specific, could be an important model for better understanding the mechanisms involved in allergic and respiratory diseases. In addition, urbanization and thus reduction of the rural environment, may well explain the increased prevalence of allergies observed in the past 50 years.
- Subjects :
- Male
MESH: Immune Tolerance
Adolescent
MESH: Hypersensitivity
MESH: Air Pollutants
MESH: Environmental Exposure
MESH: Disease Susceptibility
Rural Health
MESH: Models, Immunological
MESH: Prenatal Exposure Delayed Effects
MESH: Pregnancy
Pregnancy
MESH: Child
Hypersensitivity
Immune Tolerance
Prevalence
Respiratory Hypersensitivity
Animals
Humans
MESH: Animals
MESH: Animals, Domestic
Genetic Predisposition to Disease
Child
MESH: Prevalence
MESH: Adolescent
Air Pollutants
MESH: Humans
MESH: Child, Preschool
MESH: Genetic Predisposition to Disease
Models, Immunological
Agriculture
Environmental Exposure
MESH: Rural Health
MESH: Male
MESH: Milk
MESH: Virus Diseases
MESH: Respiratory Hypersensitivity
Milk
Virus Diseases
Air Pollution, Indoor
Animals, Domestic
Child, Preschool
Prenatal Exposure Delayed Effects
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Female
Disease Susceptibility
MESH: Air Pollution, Indoor
MESH: Female
MESH: Agriculture
Subjects
Details
- Language :
- French
- ISSN :
- 17762588 and 07618425
- Volume :
- 27
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Revue des maladies respiratoires
- Accession number :
- edsair.pmid.dedup....0b349a9cd235decde0c970528b286582