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MetaboSignal, a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways

Authors :
Rodriguez-Martinez, Andrea
Ayala, Rafael
Posma, Joram M.
Neves, Ana L.
Gauguier, Dominique
Nicholson, Jeremy K.
Dumas, Marc-Emmanuel
Source :
Bioinformatics
Publication Year :
2016
Publisher :
Oxford University Press, 2016.

Abstract

Summary: MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes. Availability and Implementation: MetaboSignal is available from Bioconductor: https://bioconductor.org/packages/MetaboSignal/ Contact: m.dumas@imperial.ac.uk. Supplementary information: Supplementary data are available at Bioinformatics online.

Details

Database :
OpenAIRE
Journal :
Bioinformatics
Accession number :
edsair.pmid.dedup....15c5d17c6fe45bff56f204459046e9a7