Back to Search Start Over

A novel soft tissue prediction methodology for orthognathic surgery based on probabilistic finite element modelling

Authors :
Knoops, Paul G. M.
Borghi, Alessandro
Ruggiero, Federica
Badiali, Giovanni
Bianchi, Alberto
Marchetti, Claudio
Rodriguez-Florez, Naiara
Breakey, Richard W. F.
Jeelani, Owase
Dunaway, David J.
Schievano, Silvia
Knoops PGM, Borghi A, Ruggiero F, Badiali G, Bianchi A, Marchetti C, Rodriguez-Florez N, Breakey RWF, Jeelani O, Dunaway DJ, Schievano S
Source :
PLoS ONE, Vol 13, Iss 5, p e0197209 (2018), PLoS ONE
Publication Year :
2018
Publisher :
Public Library of Science (PLoS), 2018.

Abstract

Repositioning of the maxilla in orthognathic surgery is carried out for functional and aesthetic purposes. Pre-surgical planning tools can predict 3D facial appearance by computing the response of the soft tissue to the changes to the underlying skeleton. The clinical use of commercial prediction software remains controversial, likely due to the deterministic nature of these computational predictions. A novel probabilistic finite element model (FEM) for the prediction of postoperative facial soft tissues is proposed in this paper. A probabilistic FEM was developed and validated on a cohort of eight patients who underwent maxillary repositioning and had pre- and postoperative cone beam computed tomography (CBCT) scans taken. Firstly, a variables correlation assessed various modelling parameters. Secondly, a design of experiments (DOE) provided a range of potential outcomes based on uniformly distributed input parameters, followed by an optimisation. Lastly, the second DOE iteration provided optimised predictions with a probability range. A range of 3D predictions was obtained using the probabilistic FEM and validated using reconstructed soft tissue surfaces from the postoperative CBCT data. The predictions in the nose and upper lip areas accurately include the true postoperative position, whereas the prediction under-estimates the position of the cheeks and lower lip. A probabilistic FEM has been developed and validated for the prediction of the facial appearance following orthognathic surgery. This method shows how inaccuracies in the modelling and uncertainties in executing surgical planning influence the soft tissue prediction and it provides a range of predictions including a minimum and maximum, which may be helpful for patients in understanding the impact of surgery on the face.

Details

Language :
English
ISSN :
19326203
Volume :
13
Issue :
5
Database :
OpenAIRE
Journal :
PLoS ONE
Accession number :
edsair.pmid.dedup....4f18f17557bdbafaa2ece984150bf405