Back to Search
Start Over
Impella Support for Acute Myocardial Infarction Complicated by Cardiogenic Shock
- Source :
- Schrage, B, Ibrahim, K, Loehn, T, Werner, N, Sinning, J M, Pappalardo, F, Pieri, M, Skurk, C, Lauten, A, Landmesser, U, Westenfeld, R, Horn, P, Pauschinger, M, Eckner, D, Twerenbold, R, Nordbeck, P, Salinger, T, Abel, P, Empen, K, Busch, M C, Felix, S B, Sieweke, J T, Møller, J E, Pareek, N, Hill, J, MacCarthy, P, Bergmann, M W, Henriques, J P S, Möbius-Winkler, S, Schulze, P C, Ouarrak, T, Zeymer, U, Schneider, S, Blankenberg, S, Thiele, H, Schäfer, A & Westermann, D 2019, ' Impella Support for Acute Myocardial Infarction Complicated by Cardiogenic Shock ', Circulation, vol. 139, no. 10, pp. 1249-1258 . https://doi.org/10.1161/CIRCULATIONAHA.118.036614
- Publication Year :
- 2018
-
Abstract
- BACKGROUND: Percutaneous mechanical circulatory support devices are increasingly used in acute myocardial infarction complicated by cardiogenic shock (AMI-CS), despite limited evidence for their effectiveness. The aim of this study was to evaluate outcomes associated with use of the Impella device compared with intra-aortic balloon pump (IABP) and medical treatment in patients with AMI-CS. METHODS: Data of patients with AMI-CS treated with the Impella device at European tertiary care hospitals were collected retrospectively. All patients underwent early revascularization and received optimal medical treatment. Using IABP-SHOCK II (Intraaortic Balloon Pump in Cardiogenic Shock II) trial inclusion and exclusion criteria, 372 patients were identified and included in this analysis. These patients were matched to 600 patients from the IABP-SHOCK II trial. The following baseline criteria were used as matching parameters: age, sex, mechanical ventilation, ejection fraction, prior cardiopulmonary resuscitation, and lactate. Primary end point was 30-day all-cause mortality. RESULTS: In total, 237 patients treated with an Impella could be matched to 237 patients from the IABP-SHOCK II trial. Baseline parameters were similarly distributed after matching. There was no significant difference in 30-day all-cause mortality (48.5% versus 46.4%, P=0.64). Severe or life-threatening bleeding (8.5% versus 3.0%, P
- Subjects :
- Male
Time Factors
Myocardial Infarction
Shock, Cardiogenic
shock
Impella
Prosthesis Design
cardiopulmonary resuscitation
shock, cardiogenic
Risk Factors
cardiogenic
Myocardial Revascularization
Humans
Registries
Aged
Retrospective Studies
Intra-Aortic Balloon Pumping
intraaortic balloon pumping
Cardiovascular Agents
Recovery of Function
Middle Aged
Europe
myocardial infarction
Treatment Outcome
Female
Heart-Assist Devices
Subjects
Details
- ISSN :
- 15244539
- Volume :
- 139
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Circulation
- Accession number :
- edsair.pmid.dedup....7e249d7c0f7bf5818bd2792bd9a9fff9