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The impact of position-orientation adaptive smoothing in diffusion weighted imaging—From diffusion metrics to fiber tractography
- Source :
- PLoS ONE, PLoS ONE, Vol 15, Iss 5, p e0233474 (2020)
- Publication Year :
- 2020
- Publisher :
- Public Library of Science, 2020.
-
Abstract
- In contrast to commonly used approaches to improve data quality in diffusion weighted imaging, position-orientation adaptive smoothing (POAS) provides an edge-preserving post-processing approach. This study aims to investigate its potential and effects on image quality, diffusion metrics, and fiber tractography of the corticospinal tract in relation to non-post-processed and averaged data. 22 healthy volunteers were included in this study. For each volunteer five clinically applicable diffusion weighted imaging data sets were acquired and post-processed by standard averaging and POAS. POAS post-processing led to significantly higher signal-to-noise-ratios (p < 0.001), lower fractional anisotropy across the whole brain (p < 0.05) and reduced intra-subject variability of diffusion weighted imaging signal intensity and fractional anisotropy (p < 0.001, p = 0.006). Fiber tractography of the corticospinal tract resulted in significantly (p = 0.027, p = 0.014) larger tract volumes while fiber density was the lowest. Similarity across tractography results was highest for POAS post-processed data (p < 0.001). POAS post-processing enhances image quality, decreases the intra-subject variability of signal intensity and fractional anisotropy, increases fiber tract volume of the corticospinal tract, and leads to higher reproducibility of tractography results. Thus, POAS post-processing supports a reliable and more accurate fiber tractography of the corticospinal tract, being mandatory for the clinical use.
- Subjects :
- Central Nervous System
Adult
Computer and Information Sciences
Imaging Techniques
Science
Brain Morphometry
Materials Science
Material Properties
Pyramidal Tracts
Neuroimaging
Research and Analysis Methods
Nervous System
Diagnostic Radiology
Diagnostic Medicine
Medicine and Health Sciences
Image Processing, Computer-Assisted
Humans
Orientation, Spatial
Observer Variation
Brain Mapping
Diffusion Weighted Imaging
Radiology and Imaging
Physics
Biology and Life Sciences
Brain
Reproducibility of Results
Research Assessment
Condensed Matter Physics
Magnetic Resonance Imaging
Reproducibility
Healthy Volunteers
Diffusion Tensor Imaging
Data Acquisition
Diffusion Magnetic Resonance Imaging
Physical Sciences
Medicine
Anisotropy
Anatomy
Tractography
Research Article
Neuroscience
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 15
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.pmid.dedup....8345086e3824d583c667af2ea8c67698